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脓毒症诱导免疫抑制的切卡结扎和穿刺和鼻内感染双重模型的设计
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June 15, 2019
DOI:
1West China School of Basic Medical Sciences & Forensic Medicine,Sichuan University, 2Department of Biomedical Sciences, School of Medicine and Health Sciences,University of North Dakota, 3State Key Laboratory of Trauma, Burns and Combined Injury, Institute of Surgery Research, Daping Hospital,Army Medical University
Summary
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该协议描述了在免疫抑制条件下测量继发医院感染的传染性结果的技术,首先通过建立结扎/穿刺小鼠,然后挑战他们与鼻内感染创建一个临床相关的免疫抑制败血症模型。
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Cite this Article
Wang, Z., Pu, Q., Lin, P., Li, C., Jiang, J., Wu, M. Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression. J. Vis. Exp. (148), e59386, doi:10.3791/59386 (2019).
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