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活小鼠肠道移植物对宿主病的诱导及微内窥镜评价
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JoVE 신문 면역학 및 감염병학
Induction of Intestinal Graft-versus-host Disease and Its Mini-endoscopic Assessment in Live Mice
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活小鼠肠道移植物对宿主病的诱导及微内窥镜评价

9,376 Views

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09:50 min

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February 11, 2019

DOI:

10.3791/58871-v

DOI:
10.3791/58871-v

•

09:50 min
February 11, 2019

•

17 Views
, , , ,
1Department of Internal Medicine 1, University Erlangen-Nürnberg,University Hospital Erlangen, 2Institute of Pathology, Department of Nephropathology,University Hospital Erlangen, 3Deutsches Zentrum Immuntherapie (DZI),University Hospital Erlangen

Summary

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在这里, 我们提出了一个协议, 描述异基因造血干细胞移植, 并允许重复的微内窥镜评估远端结肠原位的存在, 特点, 和严重程度的结肠炎症在生活患有肠道移植物抗宿主病的小鼠。

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Buchele, V., Büttner-Herold, M., Vogler, T., Neurath, M. F., Hildner, K. Induction of Intestinal Graft-versus-host Disease and Its Mini-endoscopic Assessment in Live Mice. J. Vis. Exp. (144), e58871, doi:10.3791/58871 (2019).

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