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Induction of Intestinal Graft-versus-host Disease and Its Mini-endoscopic Assessment in Live Mice
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Induction of Intestinal Graft-versus-host Disease and Its Mini-endoscopic Assessment in Live Mice
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February 11, 2019
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Here, we present a protocol that describes allogeneic hematopoietic stem cell transplantation and allows repetitive mini-endoscopic evaluations of the distal colon in situ for the presence, characteristics, and severity of colonic inflammation within live mice suffering from intestinal graft-versus-host disease.
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Buchele, V., Büttner-Herold, M., Vogler, T., Neurath, M. F., Hildner, K. Induction of Intestinal Graft-versus-host Disease and Its Mini-endoscopic Assessment in Live Mice. J. Vis. Exp. (144), e58871, doi:10.3791/58871 (2019).
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