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Immunology and Infection

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JoVE Journal Immunology and Infection
Kwantificering van Efferocytosis door eencellige fluorescentie microscopie
 
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Kwantificering van Efferocytosis door eencellige fluorescentie microscopie

Article DOI: 10.3791/58149-v • 06:15 min • August 18th, 2018
August 18th, 2018 •
1, 1, 2,3, 1
1Department of Microbiology and Immunology and the Center for Human Immunology, University of Western Ontario, 2Institute of Infection and Global Health, University of Liverpool, 3Department of Respiratory Research, Aintree University Hospital NHS Foundation Trust

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Efferocytosis, de fagocytische verwijdering van apoptotic cellen, is nodig om de homeostase te handhaven en wordt vergemakkelijkt door de receptoren en signaalroutes waarmee voor de erkenning, de engulfment, en de internalisering van de apoptotic cellen. Hierin presenteren wij een fluorescentie microscopie protocol voor de kwantificering van efferocytosis en de activiteit van efferocytic signaalroutes.

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Immunologie en infecties probleem 138 Efferocytosis fagocytose apoptosis microscopie fagocytensysteem macrofaag
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