03:09Placing the Vestibular or the Auditory Sensory Organ in a Collagen I Gel
04:45Viral Injections in Three-dimensional Cultures of Vestibular and Auditory Sensory Organs
06:06Results: Use of Three-dimensional Organotypic Culture in Collagen I Gel to Study the Architecture and Viral Infections of the Vestibular and Cochlear Sensory Organs
Three-dimensional organotypic cultures of the murine utricle and cochlea in optically clear collagen I gels preserve innate tissue morphology, allow for mechanical stimulation through adjustment of matrix stiffness, and permit virus-mediated gene delivery.