In this work, a protocol for signal enhancement of nanoprobe-based biosensing is presented. The protocol is based on the reduction of chloroauric acid onto the surface of existing nanoprobes that consist of gold, silver, silica or iron-oxide nanoparticles.
Dias, J. T., Svedberg, G., Nystrand, M., Andersson-Svahn, H., Gantelius, J. Rapid Nanoprobe Signal Enhancement by In Situ Gold Nanoparticle Synthesis. J. Vis. Exp. (133), e57297, doi:10.3791/57297 (2018).