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Journal / Genetics / Detectie van Copy Number Wijzigingen met behulp…
JoVE Journal
Genetics

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JoVE Journal Genetics
Detectie van Copy Number Wijzigingen met behulp van Single Cell Sequencing
 
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Detectie van Copy Number Wijzigingen met behulp van Single Cell Sequencing

Article DOI: 10.3791/55143-v • 09:45 min • February 17th, 2017
February 17th, 2017 •
1,2,3, 4, 5
1Koch Institute for Integrative Cancer Research, Department of Biology, Massachusetts Institute of Technology, 2Howard Hughes Medical Institute, 3Division of Health Sciences and Technology, Harvard Medical School, 4The Barbara K. Ostrom (1978) Bioinformatics and Computing Facility in the Swanson Biotechnology Center, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 5BioMicro Center, Department of Biology, Massachusetts Institute of Technology

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Enkele cel sequencing is een steeds populairder en toegankelijk instrument voor de aanpak van genomische veranderingen op hoge resolutie. Wij bieden een protocol dat enkele cel sequencing gebruikt om het aantal kopieën veranderingen te identificeren in enkele cellen.

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Genetics aantal kopieën wijziging aneuploïdie genomische heterogeniteit enkele cel hele genoom amplificatie whole genome sequencing
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