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면역 적격 설치류에서 강력한 폐렴 모델에 대해 항균 효능을 평가하기<i> S. 폐렴</i><i> H. 인플루엔자</i><i> K. 폐렴</i><em> P. 녹농균</em> 또는<em>를했다. baumannii가</em
JoVE 신문
면역학 및 감염병학
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JoVE 신문 면역학 및 감염병학
A Robust Pneumonia Model in Immunocompetent Rodents to Evaluate Antibacterial Efficacy against S. pneumoniae, H. influenzae, K. pneumoniae, P. aeruginosa or A. baumannii

면역 적격 설치류에서 강력한 폐렴 모델에 대해 항균 효능을 평가하기<i> S. 폐렴</i><i> H. 인플루엔자</i><i> K. 폐렴</i><em> P. 녹농균</em> 또는<em>를했다. baumannii가</em

DOI:

09:17 min

January 02, 2017

, , , , ,

Chapters

  • 00:05Title
  • 01:13Prepare Saline Bacterial Suspensions and Agar-based Inoculum
  • 02:20Prepare Intubation Device, Intubate and Inoculate Rats
  • 05:47Prepare Intubation Device, Intubate, and Inoculate Mice
  • 07:10Results: Evaluation of Antibacterial Efficacy in Infected Rats and Mice
  • 08:37Conclusion

Summary

자동 번역

A method for establishing lung infections in immunocompetent rodents is described. With proficiency, this method can be performed quickly and easily to induce stable infection with many isolates of S. pneumoniae, H. influenzae, P. aeruginosa, K. pneumoniae and A. baumannii.

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