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A Portal Vein Injection Model to Study Liver Metastasis of Breast Cancer
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December 26, 2016
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A surgical procedure was developed to deliver mammary tumor cells to the murine liver via portal vein injection. This model permits investigation of late stages of liver metastasis in a fully immune competent host, including tumor cell extravasation, seeding, survival, and metastatic outgrowth in the liver.
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Goddard, E. T., Fischer, J., Schedin, P. A Portal Vein Injection Model to Study Liver Metastasis of Breast Cancer. J. Vis. Exp. (118), e54903, doi:10.3791/54903 (2016).
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