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A Portal Vein Injection Model to Study Liver Metastasis of Breast Cancer
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がん研究
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JoVE Journal がん研究
A Portal Vein Injection Model to Study Liver Metastasis of Breast Cancer

A Portal Vein Injection Model to Study Liver Metastasis of Breast Cancer

DOI:
10.3791/54903-v

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07:35 min

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December 26, 2016

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, ,
1Department of Cell, Developmental and Cancer Biology,Oregon Health and Science University

章

  • 00:05標題
  • 00:59Portal Vein Injection
  • 04:37Results: Representative Portal Vein Tumor Cell Delivery Analyses
  • 06:26Conclusion

概要

自動翻訳

自動翻訳

A surgical procedure was developed to deliver mammary tumor cells to the murine liver via portal vein injection. This model permits investigation of late stages of liver metastasis in a fully immune competent host, including tumor cell extravasation, seeding, survival, and metastatic outgrowth in the liver.

タグ

Portal Vein InjectionLiver MetastasisBreast CancerTumor CellsMurine ModelMetastatic CascadeCell ExtravasationCell SeedingCell DeathCell ProliferationCell DormancySurgical ProcedureAnatomical SurveillanceBalb/c MiceAnalgesiaDisinfectionIncisionTumor Cell Injection

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