Journal
/
신경과학
/
ナノ粒子神経毒性を決定するために、代理バイオセンサーとしてミクログリア
JoVE 신문
신경과학
JoVE 비디오를 활용하시려면 도서관을 통한 기관 구독이 필요합니다.  전체 비디오를 보시려면 로그인하거나 무료 트라이얼을 시작하세요.
JoVE 신문 신경과학
Microglia as a Surrogate Biosensor to Determine Nanoparticle Neurotoxicity
Please note that all translations are automatically generated. Click here for the English version.

ナノ粒子神経毒性を決定するために、代理バイオセンサーとしてミクログリア

6,831 Views

•

08:37 min

•

October 25, 2016

DOI:

10.3791/54662-v

DOI:
10.3791/54662-v

•

08:37 min
October 25, 2016

•

1 Views
, , , , ,
1Minneapolis Veterans Affairs Health Care System, 2Department of Food Science and Nutrition,University of Minnesota, 3Biomedical Informatics and Computational Biology Program,University of Minnesota, 4Minnesota Obesity Center,University of Minnesota

Summary

Automatically generated

Microglia (immune cells of the brain), are used as a surrogate biosensor to determine how nanoparticles influence neurotoxicity. We describe a series of experiments designed to assay microglial response to nanoparticles and exposure of hypothalamic neurons to supernatant from activated microglia to determine neurotoxicity.

Explore More Videos

MicrogliaBiosensorNanoparticleNeurotoxicity신경과학In VitroCell CultureBV2 CellsSilver NanoparticlesConditioned MediaFiltrationCell CountingCell SeedingCell StarvationCell Activation

Read Article

Cite this Article

Duffy, C. M., Ahmed, S., Yuan, C., Mavanji, V., Nixon, J. P., Butterick, T. Microglia as a Surrogate Biosensor to Determine Nanoparticle Neurotoxicity. J. Vis. Exp. (116), e54662, doi:10.3791/54662 (2016).

Download .ris file

Copy

Share Video

.

Copy