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A Method for Evaluating the Reinforcing Properties of Ethanol in Rats without Water Deprivation, Saccharin Fading or Extended Access Training
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A Method for Evaluating the Reinforcing Properties of Ethanol in Rats without Water Deprivation, Saccharin Fading or Extended Access Training

A Method for Evaluating the Reinforcing Properties of Ethanol in Rats without Water Deprivation, Saccharin Fading or Extended Access Training

9,236 Views

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07:50 min

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January 29, 2017

DOI:

10.3791/53305-v

DOI:
10.3791/53305-v

•

07:50 min
January 29, 2017

•

2 Views
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1Center for Social and Affective Neuroscience, IKE,Linköping University, 2Laboratory of Clinical and Translational Studies, National Institute on Alcohol Abuse and Alcoholism,National Institutes of Health

Summary

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This protocol describes a novel and efficient method to quickly initiate operant responding for ethanol in rats that, contrary to standard methods, does not require water deprivation or saccharin/sucrose fading to initiate responding.

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EthanolAlcoholOperant RespondingSelf-administrationRatsWater DeprivationSaccharin FadingExtended Access TrainingRewardNeurobiologyNeuropharmacologyAlcohol SeekingConditioningOperant ChamberLever PressingEthanol Solution

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Cite this Article

Augier, E., Dulman, R. S., Singley, E., Heilig, M. A Method for Evaluating the Reinforcing Properties of Ethanol in Rats without Water Deprivation, Saccharin Fading or Extended Access Training. J. Vis. Exp. (119), e53305, doi:10.3791/53305 (2017).

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