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A Method for Evaluating the Reinforcing Properties of Ethanol in Rats without Water Deprivation, Saccharin Fading or Extended Access Training
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A Method for Evaluating the Reinforcing Properties of Ethanol in Rats without Water Deprivation, Saccharin Fading or Extended Access Training

A Method for Evaluating the Reinforcing Properties of Ethanol in Rats without Water Deprivation, Saccharin Fading or Extended Access Training

DOI:
10.3791/53305-v

•

07:50 min

•

January 29, 2017

•

, , ,
1Center for Social and Affective Neuroscience, IKE,Linköping University, 2Laboratory of Clinical and Translational Studies, National Institute on Alcohol Abuse and Alcoholism,National Institutes of Health

Chapters

  • 00:05Title
  • 00:51Animal Care and Operant Conditioning Chamber Setup
  • 03:02Operant Conditioning Sessions
  • 04:08Manipulating Conditioned Rats
  • 05:49Using Naltrexone to Diminish Alcoholism in Rats
  • 06:46Conclusion

Summary

自动翻译

自动翻译

This protocol describes a novel and efficient method to quickly initiate operant responding for ethanol in rats that, contrary to standard methods, does not require water deprivation or saccharin/sucrose fading to initiate responding.

Tags

EthanolAlcoholOperant RespondingSelf-administrationRatsWater DeprivationSaccharin FadingExtended Access TrainingRewardNeurobiologyNeuropharmacologyAlcohol SeekingConditioningOperant ChamberLever PressingEthanol Solution

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