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Eye Irritation Test (EIT) for Hazard Identification of Eye Irritating Chemicals using Reconstructed Human Cornea-like Epithelial (RhCE) Tissue Model
Chapters
- 00:05Title
- 01:43Reconstructed Human Cornea-like Epithelial (RhCE) Tissue Treatment Preparation (Day 0)
- 03:08Pre-treatment and Test Article Exposure (Day 1)
- 04:42Rinsing
- 06:13MTT Viability Assay (Liquid Test Day 1; Solid Test Day 2)
- 08:19Results: Representative EIT Results for 10 Test Articles
- 09:36Conclusion
We have developed an eye irritation test which utilizes a three dimensional reconstructed human cornea-like epithelial (RhCE) tissue model. The test is able to discriminate between ocular irritant and corrosive materials (GHS Categories 1 and 2 combined) and those that do not require labeling (GHS No Category).
