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Eye Irritation Test (EIT) for Hazard Identification of Eye Irritating Chemicals using Reconstructed Human Cornea-like Epithelial (RhCE) Tissue Model
JoVE Journal
Bioengineering
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JoVE Journal Bioengineering
Eye Irritation Test (EIT) for Hazard Identification of Eye Irritating Chemicals using Reconstructed Human Cornea-like Epithelial (RhCE) Tissue Model

Eye Irritation Test (EIT) for Hazard Identification of Eye Irritating Chemicals using Reconstructed Human Cornea-like Epithelial (RhCE) Tissue Model

English

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36,254 Views

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10:13 min

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August 23, 2015

DOI:

10.3791/52979-v

DOI:
10.3791/52979-v

•

10:13 min
August 23, 2015

•

37 Views
, , , ,
1MatTek Corporation, 2MatTek In Vitro Life Science Laboratories

Summary

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We have developed an eye irritation test which utilizes a three dimensional reconstructed human cornea-like epithelial (RhCE) tissue model. The test is able to discriminate between ocular irritant and corrosive materials (GHS Categories 1 and 2 combined) and those that do not require labeling (GHS No Category).

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Cite this Article

Kaluzhny, Y., Kandárová, H., d’Argembeau-Thornton, L., Kearney, P., Klausner, M. Eye Irritation Test (EIT) for Hazard Identification of Eye Irritating Chemicals using Reconstructed Human Cornea-like Epithelial (RhCE) Tissue Model. J. Vis. Exp. (102), e52979, doi:10.3791/52979 (2015).

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