JoVE 비디오를 활용하시려면 도서관을 통한 기관 구독이 필요합니다. 전체 비디오를 보시려면 로그인하거나 무료 트라이얼을 시작하세요.
Quantitative Analysis of Climbing Defects in a Drosophila Model of Neurodegenerative Disorders
18,019 Views
•
06:30 min
•
June 13, 2015
DOI:
Summary
Automatically generated
We present an optimized inexpensive and reliable negative geotaxis assay in Drosophila melanogaster as a model for neurodegenerative disorders. Being more sensitive to mild locomotor defects, this assay will help screen for potential genetic interactions and drug targets.
Read Article
Cite this Article
Madabattula, S. T., Strautman, J. C., Bysice, A. M., O’Sullivan, J. A., Androschuk, A., Rosenfelt, C., Doucet, K., Rouleau, G., Bolduc, F. Quantitative Analysis of Climbing Defects in a Drosophila Model of Neurodegenerative Disorders. J. Vis. Exp. (100), e52741, doi:10.3791/52741 (2015).
Copy