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A Mouse Model for Pathogen-induced Chronic Inflammation at Local and Systemic Sites
JoVE 비디오를 활용하시려면 도서관을 통한 기관 구독이 필요합니다. 전체 비디오를 보시려면 로그인하거나 무료 트라이얼을 시작하세요.
Chapters
- 00:05Title
- 01:55Growth and Cultivation of Bacteria
- 03:25MRI Data Acquisition
- 05:00Aorta Pinning
- 06:07Lipid Staining and Lesion Quantification
- 07:27Results: Pathogen-induced Chronic Inflammation at Local and Systemic Sites
- 08:52Conclusion
Animal models have proven to be invaluable tools in defining host and pathogen specific mechanisms that contribute to the development of chronic inflammation. Here we describe a mouse model of oral infection with the human pathogen Porphyromonas gingivalis and detail methodologies to assess the progression of inflammation at local and systemic sites.
