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A Mouse Model for Pathogen-induced Chronic Inflammation at Local and Systemic Sites
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A Mouse Model for Pathogen-induced Chronic Inflammation at Local and Systemic Sites
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09:52 min
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August 08, 2014
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Animal models have proven to be invaluable tools in defining host and pathogen specific mechanisms that contribute to the development of chronic inflammation. Here we describe a mouse model of oral infection with the human pathogen Porphyromonas gingivalis and detail methodologies to assess the progression of inflammation at local and systemic sites.
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Papadopoulos, G., Kramer, C. D., Slocum, C. S., Weinberg, E. O., Hua, N., Gudino, C. V., Hamilton, J. A., Genco, C. A. A Mouse Model for Pathogen-induced Chronic Inflammation at Local and Systemic Sites. J. Vis. Exp. (90), e51556, doi:10.3791/51556 (2014).
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