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Journal / Neuroscience / 诱导星形胶质细胞受体的可塑性由神经元的放电频率操作…
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Neuroscience

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JoVE Journal Neuroscience
诱导星形胶质细胞受体的可塑性由神经元的放电频率操作
 
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诱导星形胶质细胞受体的可塑性由神经元的放电频率操作

Article DOI: 10.3791/51458-v • 12:47 min • March 20th, 2014
March 20th, 2014 •
1, 1, 1, 1, 2,3
1Graduate Program in Neuroscience, University of California Riverside, 2Department of Cell Biology and Neuroscience, University of California Riverside, 3Center for Glial-Neuronal Interactions, University of California Riverside

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在这里，我们描述了用于诱导稳态可塑性神经元星形胶质细胞的G蛋白偶联受体的可塑性研究方案的适应。最近用于检查变化星形细胞组I型mGluRs在幼年小鼠中，该方法可以应用于测量各种星形细胞G蛋白偶联受体的比例，在从成年小鼠原位和体内组织，并更好地欣赏星形细胞受体的敏感性的变化的神经元活性。

Tags

神经科学，第85，星形胶质细胞，可塑性，mGluRs的，神经元放电，电，Gq蛋白G蛋白偶联受体，丸装，钙，微区，急性切片，海马，鼠标
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