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RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma
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March 11, 2014
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The presence of high-risk HPV in head and neck tumor tissue is associated with favorable outcomes. The recently developed RNA in situ hybridization technique called RNAscope allows direct visualization of HPV E6/E7 mRNA in FFPE tissue sections.
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Wang, H., Wang, M. X., Su, N., Wang, L., Wu, X., Bui, S., Nielsen, A., Vo, H., Nguyen, N., Luo, Y., Ma, X. RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma. J. Vis. Exp. (85), e51426, doi:10.3791/51426 (2014).
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