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小脑颗粒神经元的遗传操作<em>体外</em>和<em>在体内</em>为研究神经元形态和迁移

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Genetic Manipulation of Cerebellar Granule Neurons In Vitro and In Vivo to Study Neuronal Morphology and Migration

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小脑颗粒神经元的遗传操作<em>体外</em>和<em>在体内</em>为研究神经元形态和迁移

13,578 Views

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09:07 min

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March 17, 2014

DOI:

10.3791/51070-v

DOI:

10.3791/51070-v

•

09:07 min

March 17, 2014

•

1 Views

Anna Holubowska^1,2, Chaitali Mukherjee^1,2, Mayur Vadhvani^1,2, Judith Stegmüller^1,2

¹Cellular and Molelcular Neurobiology,Max Planck Institute of Experimental Medicine, ²Center for Nanoscale Microscopy and Molecular Physiology of the Brain (CNMPB)

Summary

神经元的形态发生和迁移的基本正常的大脑发育至关重要的事件。在这里，我们描述的方法来操纵基因培养的小脑颗粒神经元和小脑发展的形态和神经元的迁徙特性的评估。

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