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Assays for the Identification of Novel Antivirals against Bluetongue Virus
Chapters
- 00:05Title
- 01:37Cytopathic Effect Based Assay Using the CellTiterGlo Kit
- 03:31Dose Response Assay
- 06:28Time-of-Addition Assay
- 08:55Representative Antiviral Compound Assay Results
- 11:34Conclusion
Three assays, including the cytopathic effect (CPE)-based assay, dose-response assay and Time-of-Addition (ToA) assay have been developed, optimized, validated and utilized to identify novel antivirals against Bluetongue virus (BTV), as well as to determine the possible Mechanism-of-Action (MoA) for newly identified antivirals.
