Journal
/
Immunology and Infection
/
Assays for the Identification of Novel Antivirals against Bluetongue Virus
JoVE Journal
Immunology and Infection
A subscription to JoVE is required to view this content.  Sign in or start your free trial.
JoVE Journal Immunology and Infection
Assays for the Identification of Novel Antivirals against Bluetongue Virus

Assays for the Identification of Novel Antivirals against Bluetongue Virus

English

Automatically Generated

13,805 Views

•

12:02 min

•

October 11, 2013

DOI:

10.3791/50820-v

DOI:
10.3791/50820-v

•

12:02 min
October 11, 2013

•

5 Views
, ,
1Division of Infectious Diseases, Department of Medicine,University of Alabama at Birmingham, 2Molette Laboratory for Drug Discovery, Department of Chemistry and Biochemistry,Auburn University

Summary

Automatically generated

Three assays, including the cytopathic effect (CPE)-based assay, dose-response assay and Time-of-Addition (ToA) assay have been developed, optimized, validated and utilized to identify novel antivirals against Bluetongue virus (BTV), as well as to determine the possible Mechanism-of-Action (MoA) for newly identified antivirals.

Explore More Videos

Antiviral AssaysBTV AntiviralsCytopathic Effect (CPE) AssayDose-response AssayMechanism Of Action (ToA) AssayAntiviral ScreeningViral LifecycleCell Culture System

Read Article

Cite this Article

Gu, L., Schneller, S. W., Li, Q. Assays for the Identification of Novel Antivirals against Bluetongue Virus. J. Vis. Exp. (80), e50820, doi:10.3791/50820 (2013).

Download .ris file

Copy

Share Video

.

Copy