JoVE 비디오를 활용하시려면 도서관을 통한 기관 구독이 필요합니다. 전체 비디오를 보시려면 로그인하거나 무료 트라이얼을 시작하세요.
Chapters
- 00:05Title
- 02:08Lateral Fluid Percussion Injury
- 03:04Behavioral Analysis- Conditioned Fear Response
- 03:42Acute Hippocampal Slice Preparation
- 04:41Extracellular Field Potential Recording and Visualized Patch-clamp Recording
- 06:43Voltage Sensitive Dye Imaging
- 08:39Results: Alterations of Hippocampal Circuit Function Following Mild Traumatic Brain Injury
- 10:33Conclusion
Un enfoque multifacético para investigar cambios funcionales en los circuitos del hipocampo se explica. Técnicas electrofisiológicas se describen junto con el protocolo de lesión, las pruebas de comportamiento y método de disección regional. La combinación de estas técnicas se pueden aplicar de forma similar para otras regiones del cerebro y preguntas científicas.
Tags
InvestigationsAlterationsHippocampal Circuit FunctionMild Traumatic Brain InjuryTBINeurological ImpairmentsMemory DeficitsSeizure ThresholdHippocampal DysfunctionLateral Fluid Percussion InjuryAnimal ModelNeuronal Cell LossGliosisIonic PerturbationCombinatorial MethodEx Vivo Physiological TechniquesAnimal Behavior AnalysisBiochemical AnalysisCognitive DisabilityExtracellular Field Potential RecordingWhole-cell Patch-clampingVoltage Sensitive Dye RecordingRegionally Dissecting Subregions Of The HippocampusNeurochemical AnalysisMetabolic Analysis
