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Investigations on Alterations of Hippocampal Circuit Function Following Mild Traumatic Brain Injury
Chapters
- 00:05Title
- 02:08Lateral Fluid Percussion Injury
- 03:04Behavioral Analysis- Conditioned Fear Response
- 03:42Acute Hippocampal Slice Preparation
- 04:41Extracellular Field Potential Recording and Visualized Patch-clamp Recording
- 06:43Voltage Sensitive Dye Imaging
- 08:39Results: Alterations of Hippocampal Circuit Function Following Mild Traumatic Brain Injury
- 10:33Conclusion
A multi-faceted approach to investigating functional changes to hippocampal circuitry is explained. Electrophysiological techniques are described along with the injury protocol, behavioral testing and regional dissection method. The combination of these techniques can be applied in similar fashion for other brain regions and scientific questions.
Tags
InvestigationsAlterationsHippocampal Circuit FunctionMild Traumatic Brain InjuryTBINeurological ImpairmentsMemory DeficitsSeizure ThresholdHippocampal DysfunctionLateral Fluid Percussion InjuryAnimal ModelNeuronal Cell LossGliosisIonic PerturbationCombinatorial MethodEx Vivo Physiological TechniquesAnimal Behavior AnalysisBiochemical AnalysisCognitive DisabilityExtracellular Field Potential RecordingWhole-cell Patch-clampingVoltage Sensitive Dye RecordingRegionally Dissecting Subregions Of The HippocampusNeurochemical AnalysisMetabolic Analysis
