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Human Neuroendocrine Tumor Cell Lines as a Three-Dimensional Model for the Study of Human Neuroendocrine Tumor Therapy
 

Human Neuroendocrine Tumor Cell Lines as a Three-Dimensional Model for the Study of Human Neuroendocrine Tumor Therapy

Article DOI: 10.3791/4218-v • 12:04 min • August 14th, 2012
August 14th, 2012 •
1, 1,2, 2,3, 2, 1,2
1Raymond and Beverly Sackler Foundation, 2The Cancer Institute of New Jersey, University of Medicine and Dentistry of New Jersey, 3School of Natural Sciences, Institute for Advanced Study, Princeton, New Jersey

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요약
Automatic Translation

We present a simple agarose overlay platform to grow 3D multicellular spheroids using neuroendocrine cancer cell lines. This method provides a very convenient way to examine the effect of therapeutic drugs on the neuroendocrine tumor cells. It could also help us establish human neuroendocrine tumor spheroids for cancer therapy.

Tags

Neuroendocrine Tumor Human Cell Lines Three-dimensional Model Study Therapy Incidence Malignancies Systemic Therapy Biology Therapeutic Targets Nonresectable Metastatic Neuroendocrine Tumors 3D Cell Culture Drug Screening Tumor Tissue Organization Microenvironment Multicellular Spheroids In Vitro Model Agarose-coated Plate Physiological Conditions Drug Treatments
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