This content is Free Access.
生物标志物发现的介孔二氧化硅薄膜的低分子量蛋白质富集
13,241 Views
•
13:00 min
•
April 17, 2012
DOI:
Summary
Automatically generated
我们从人体血清低分子量蛋白质和多肽的选择性恢复对介孔二氧化硅薄膜为基础的技术开发。我们的孔芯片的物理化学性能进行了微调，在肽富集提供实质性的控制，因此分析用于诊断目的的血清蛋白质。
Explore More Videos
Low Molecular Weight Protein EnrichmentMesoporous Silica Thin FilmsBiomarker DiscoveryCirculating BiomarkersEarly DiagnosisPrognosisTherapeutic EfficiencyLow Molecular Weight Proteome (LMWP)Mass Spectrometry (MS)Dynamic RangeProtein And Peptide ConcentrationsSample Pre-treatmentHighly Abundant ProteinsLow-abundance SpeciesProteomic-based ApproachesTwo-dimensional Polyacrylamide Gel-electrophoresis (2D-PAGE)Shotgun Proteomics MethodsClinical ApplicationsIsolation Of LMWP From BloodHigh Throughput ScreeningMulti-fractionation SystemMesoporous Silica Chips
Read Article
Cite this Article
Fan, J., Gallagher, J. W., Wu, H., Landry, M. G., Sakamoto, J., Ferrari, M., Hu, Y. Low Molecular Weight Protein Enrichment on Mesoporous Silica Thin Films for Biomarker Discovery. J. Vis. Exp. (62), e3876, doi:10.3791/3876 (2012).
Copy