The Colon Ascendens Stent Peritonitis (CASP) is a highly standardized model for polymicrobial abdominal sepsis in rodents. This article describes the surgical procedure of CASP. The CASP model and its variants allow the systematic investigation of various problems concerning the subject of sepsis.
Traeger, T., Koerner, P., Kessler, W., Cziupka, K., Diedrich, S., Busemann, A., Heidecke, C., Maier, S. Colon Ascendens Stent Peritonitis (CASP) - a Standardized Model for Polymicrobial Abdominal Sepsis. J. Vis. Exp. (46), e2299, doi:10.3791/2299 (2010).