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Immunology and Infection

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JoVE Journal Immunology and Infection
Colon Ascendens Stent Peritonitis (CASP) - a Standardized Model for Polymicrobial Abdominal Sepsis
 

Colon Ascendens Stent Peritonitis (CASP) - a Standardized Model for Polymicrobial Abdominal Sepsis

Article DOI: 10.3791/2299-v • 06:45 min • December 18th, 2010
December 18th, 2010 •
*1, *1, 1, 1, 1, 1, 1, 1
1Department of Surgery, University of Greifswald
* These authors contributed equally

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The Colon Ascendens Stent Peritonitis (CASP) is a highly standardized model for polymicrobial abdominal sepsis in rodents. This article describes the surgical procedure of CASP. The CASP model and its variants allow the systematic investigation of various problems concerning the subject of sepsis.

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Colon Ascendens Stent Peritonitis CASP Polymicrobial Abdominal Sepsis Sepsis Animal Models Therapeutic Approaches Scientific Questions Rodent Model Stent Insertion Intestinal Bacteria Peritonitis Bacteraemia Organ Infection Cytokines Lethality Control CASPI Variant Septic Focus Removal Clinical Practice Learnable Model Reproducible Model Clinical Course Immunology Infectiology Surgery
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