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在在线 MRI 图像的指导下,对流增强将视遗传阿德诺相关病毒载体输送到 Rhesus Macaque 的皮质
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JoVE Journal 神経科学
Convection Enhanced Delivery of Optogenetic Adeno-associated Viral Vector to the Cortex of Rhesus Macaque Under Guidance of Online MRI Images
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在在线 MRI 图像的指导下,对流增强将视遗传阿德诺相关病毒载体输送到 Rhesus Macaque 的皮质

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08:52 min

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May 23, 2019

DOI:

10.3791/59232-v

DOI:
10.3791/59232-v

•

08:52 min
May 23, 2019

•

1 Views
, , ,
1Departments of Bioengineering,University of Washington, 2Washington National Primate Research Center, 3電気・コンピュータ工学科,University of Washington, 4Department of Physiology and Center for Integrative Neuroscience,University of California, San Francisco

概要

Automatically generated

在这里,我们演示了磁共振 (MR) 引导的对流增强病毒载体到皮层 (CED) 到皮层作为一种有效和简化的方法,以实现光遗传学表达在大型皮质区域在猴脑。

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Cite this Article

Khateeb, K., Griggs, D. J., Sabes, P. N., Yazdan-Shahmorad, A. Convection Enhanced Delivery of Optogenetic Adeno-associated Viral Vector to the Cortex of Rhesus Macaque Under Guidance of Online MRI Images. J. Vis. Exp. (147), e59232, doi:10.3791/59232 (2019).

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