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Rapid Screening of HIV Reverse Transcriptase and Integrase Inhibitors
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April 09, 2014
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Here we describe cellular cytotoxicity and single round infectivity assays that allow for the rapid and accurate screening of compounds to determine their cellular cytotoxicity (CC50) and IC50 values against WT and drug resistant HIV-1.
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Smith, S. J., Hughes, S. H. Rapid Screening of HIV Reverse Transcriptase and Integrase Inhibitors. J. Vis. Exp. (86), e51400, doi:10.3791/51400 (2014).
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