Mapping Inhibitory Neuronal Circuits by Laser Scanning Photostimulation

Taruna Ikrar; Nicholas D. Olivas; Yulin Shi; Xiangmin Xu

doi:10.3791/3109

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神経科学

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Mapping Inhibitory Neuronal Circuits by Laser Scanning Photostimulation

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神経科学

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JoVE Journal 神経科学

Mapping Inhibitory Neuronal Circuits by Laser Scanning Photostimulation

17,126 Views

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09:50 min

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October 06, 2011

DOI:

10.3791/3109-v

DOI:

10.3791/3109-v

•

09:50 min

October 06, 2011

•

3 Views

Taruna Ikrar¹, Nicholas D. Olivas¹, Yulin Shi¹, Xiangmin Xu^1,2

¹Department of Anatomy and Neurobiology, School of Medicine,University of California, Irvine, ²Department of Biomedical Engineering, School of Engineering,University of California, Irvine

概要

This paper introduces an approach of combining laser scanning photostimulation with whole cell recordings in transgenic mice expressing GFP in limited inhibitory neuron populations. The technique allows for extensive mapping and quantitative analysis of local synaptic circuits of specific inhibitory cortical neurons.

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Mapping Inhibitory Neuronal Circuits by Laser Scanning Photostimulation

概要

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