Establishment of an Electrophysiological Platform for Modeling ALS with Regionally-Specific Human Pluripotent Stem Cell-Derived Astrocytes and Neurons

Arens Taga; Christa W. Habela; Alexandra Johns; Shiyu Liu; Mollie O'Brien; Nicholas J. Maragakis

doi:10.3791/62726

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建立区域特异性人多能干细胞衍生星形胶质细胞和神经元模拟ALS的电生理平台

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Neuroscienze

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JoVE Journal Neuroscienze

Establishment of an Electrophysiological Platform for Modeling ALS with Regionally-Specific Human Pluripotent Stem Cell-Derived Astrocytes and Neurons

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建立区域特异性人多能干细胞衍生星形胶质细胞和神经元模拟ALS的电生理平台

1,995 Views

•

11:52 min

•

August 26, 2021

DOI:

10.3791/62726-v

DOI:

10.3791/62726-v

•

11:52 min

August 26, 2021

•

9 Views

Arens Taga*¹, Christa W. Habela*¹, Alexandra Johns¹, Shiyu Liu¹, Mollie O’Brien¹, Nicholas J. Maragakis¹

¹Department of Neurology,Johns Hopkins University

Summary

我们描述了一种区分脊髓人诱导的多能源星形胶质细胞和神经元及其共培养以进行电生理记录的方法。

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建立区域特异性人多能干细胞衍生星形胶质细胞和神经元模拟ALS的电生理平台

Summary

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