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Behavioral Assessments of Spontaneous Locomotion in a Murine MPTP-induced Parkinson’s Disease Model
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Behavioral Assessments of Spontaneous Locomotion in a Murine MPTP-induced Parkinson’s Disease Model
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January 07, 2019
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We describe establishment of a murine model for Parkinson's disease using MPTP, and behavioral assessments using cylinder and open field tests to measure motor function. We then use L-DOPA as one example to show how to apply this model in the study of PD drugs.
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Jiang, P., Lang, Q., Yu, Q., Tang, X., Liu, Q., Li, X., Feng, X. Behavioral Assessments of Spontaneous Locomotion in a Murine MPTP-induced Parkinson's Disease Model. J. Vis. Exp. (143), e58653, doi:10.3791/58653 (2019).
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