/
/
Behavioral Assessments of Spontaneous Locomotion in a Murine MPTP-induced Parkinson’s Disease Model
Un abonnement à JoVE est nécessaire pour voir ce contenu. Connectez-vous ou commencez votre essai gratuit.
Behavioral Assessments of Spontaneous Locomotion in a Murine MPTP-induced Parkinson’s Disease Model
17,015 Views
•
05:38 min
•
January 07, 2019
DOI:
Summary
Automatically generated
We describe establishment of a murine model for Parkinson's disease using MPTP, and behavioral assessments using cylinder and open field tests to measure motor function. We then use L-DOPA as one example to show how to apply this model in the study of PD drugs.
Read Article
Cite this Article
Jiang, P., Lang, Q., Yu, Q., Tang, X., Liu, Q., Li, X., Feng, X. Behavioral Assessments of Spontaneous Locomotion in a Murine MPTP-induced Parkinson's Disease Model. J. Vis. Exp. (143), e58653, doi:10.3791/58653 (2019).
Copy