We have developed comprehensive, unbiased genome-wide screens to understand gene-drug and gene-environment interactions. Methods for screening these mutant collections are presented.
Smith, A. M., Durbic, T., Oh, J., Urbanus, M., Proctor, M., Heisler, L. E., Giaever, G., Nislow, C. Competitive Genomic Screens of Barcoded Yeast Libraries. J. Vis. Exp. (54), e2864, doi:10.3791/2864 (2011).