/
/
A Simple and Low-cost Assay for Measuring Ambulation in Mouse Models of Muscular Dystrophy
Un abonnement à JoVE est nécessaire pour voir ce contenu. Connectez-vous ou commencez votre essai gratuit.
A Simple and Low-cost Assay for Measuring Ambulation in Mouse Models of Muscular Dystrophy
9,733 Views
•
05:54 min
•
December 29, 2017
DOI:
Summary
Automatically generated
This protocol describes a flexible, low-cost system for measuring mouse ambulation in an open field activity assay. We show that a 6-minute ambulation assay based on this system detects a decrease in voluntary movement in mdx mice, and accurately distinguishes improvement in a muscle-specific rescue of these animals.
Read Article
Cite this Article
Gibbs, E. M., Crosbie-Watson, R. H. A Simple and Low-cost Assay for Measuring Ambulation in Mouse Models of Muscular Dystrophy. J. Vis. Exp. (130), e56772, doi:10.3791/56772 (2017).
Copy