/
/
Procedures for Identifying Infectious Prions After Passage Through the Digestive System of an Avian Species
Un abonnement à JoVE est nécessaire pour voir ce contenu. Connectez-vous ou commencez votre essai gratuit.
Chapitres
- 00:05Titre
- 01:56Crow Gavaging
- 05:21Mouse Inoculation and Monitoring
- 08:05Confirmation of Scrapie Diagnosis
- 10:18Results: Western Blot Analysis Confirms Diagnosis in Mice
- 11:30Conclusion
Scavengers have potential to translocate infectious transmissible spongiform encephalopathy prions in their feces to disease-free areas. We detail methods used to determine if mouse-adapted scrapie prions remain infectious after passage though the digestive tract of American crows (Corvus brachyrhynchos), a common consumer of dead animals.
