Journal
/
/
Co-localization of Cell Lineage Markers and the Tomato Signal
JoVE Revista
Biología del desarrollo
Se requiere una suscripción a JoVE para ver este contenido.  Inicie sesión o comience su prueba gratuita.
JoVE Revista Biología del desarrollo
Co-localization of Cell Lineage Markers and the Tomato Signal

Co-localization of Cell Lineage Markers and the Tomato Signal

11,942 Views

10:56 min

December 28, 2016

DOI:

10:56 min
December 28, 2016

1 Views
, , ,

Summary

Automatically generated

We developed two sets of tracing combinations in Rosa26tdtomato (ubiquitously expressed in all cells)/Cre (specifically expressed in chondrocytes) mice: one with 2.3Col1a1-GFP (specific to osteoblasts) and one with immunofluorescence (specific to bone cells). The data demonstrate the direct transformation of chondrocytes into bone cells.

Read Article