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HSV-Mediated Transgene Expression of Chimeric Constructs to Study Behavioral Function of GPCR Heteromers in Mice
 

HSV-Mediated Transgene Expression of Chimeric Constructs to Study Behavioral Function of GPCR Heteromers in Mice

Article DOI: 10.3791/53717-v • 07:30 min • July 9th, 2016
July 9th, 2016 •
1, 1, 1,2,3,4
1Department of Psychiatry, Icahn School of Medicine at Mount Sinai, 2Department of Neurology, Icahn School of Medicine at Mount Sinai, 3Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, 4Department of Physiology and Biophysics, Virginia Commonwealth University Medical School

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This article describes how to inject viral vectors into the mouse frontal cortex to test behavioral assays that require GPCR heteromeric formation.

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HSV-Mediated Transgene Expression Chimeric Constructs Behavioral Function GPCR Heteromers Mice Virus-mediated Gene Transfer Behavioral Phenotypes Neuro Pharmacology Psycho Pharmacology G-protein Coupled Receptors Molecular Level Interaction Psychiatric Disorders Schizophrenia Depression Seratonin 2a Receptor Metabotropic Glutamate Receptor 2 Mechanism Of Action Drugs For Schizophrenia Treatment Anesthesia Surgical Plane Of Anesthesia Ophthalmic Gel Stereotactic Frame Scalp Incision Pureit Clamps
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