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A Rat Model of EcoHIV Brain Infection
JoVE 杂志
神经科学
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JoVE 杂志 神经科学
A Rat Model of EcoHIV Brain Infection

A Rat Model of EcoHIV Brain Infection

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08:48 min

January 21, 2021

DOI:

08:48 min
January 21, 2021

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Summary

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Here, we present a protocol to establish a new rat model of active HIV infection using chimeric HIV (EcoHIV), which is critical for enhancing our understanding of HIV-1 viral reservoirs in the brain and offering a system to study HIV-associated neurocognitive disorders and associated comorbidities (i.e., drug abuse).

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