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Recreating the Thymic Microenvironment with iPSC-Derived Organoids
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היווצרות אורגנואידים של בלוטת התימוס האנושית בהידרוג'לים תלת מימדיים של פיברין
JoVE Journal
Developmental Biology
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JoVE Journal Developmental Biology
Formation of Human Thymus Organoids in Three-Dimensional Fibrin Hydrogels
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היווצרות אורגנואידים של בלוטת התימוס האנושית בהידרוג'לים תלת מימדיים של פיברין

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509 Views

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01:31 min

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October 04, 2024

DOI:

10.3791/66795-v

DOI:
10.3791/66795-v

•

01:31 min
October 04, 2024

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90 Views
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1Nantes Université, CHU Nantes, INSERM, Center for Research in Transplantation and Translational Immunology, UMR 1064, 2CHU Nantes, Nantes Université, Department of Pediatric and Congenital Cardiac Surgery, 3Nantes Université, CHU Nantes, INSERM, CNRS, BioCore, SFR Bonamy

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Thymus OrganoidsSelf-toleranceAutoimmunityThymic Epithelial CellsThymopoiesisCell TherapyAutoimmune DiseasesExtracellular MatrixInduced Pluripotent Stem CellsThree-dimensional HydrogelsThymocyte ProgenitorsMicroenvironment ModelingCellular CompositionOrgan TransplantationFunctional T Cell Repertoire

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Cite this Article

d'Arco, M., Provin, N., Maminirina, P., Baron, O., Guillonneau, C., David, L., Giraud, M. Formation of Human Thymus Organoids in Three-Dimensional Fibrin Hydrogels. J. Vis. Exp. (212), e66795, doi:10.3791/66795 (2024).

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