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Author Spotlight: Advancing Thymic Epithelial Cells and T-Cell Research with Human Thymic Organoids
JoVE Journal
発生生物学
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JoVE Journal 発生生物学
Formation of Human Thymus Organoids in Three-Dimensional Fibrin Hydrogels

Author Spotlight: Advancing Thymic Epithelial Cells and T-Cell Research with Human Thymic Organoids

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01:31 min

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October 04, 2024

DOI:

10.3791/66795-v

DOI:
10.3791/66795-v

•

01:31 min
October 04, 2024

•

90 Views
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1Nantes Université, CHU Nantes, INSERM, Center for Research in Transplantation and Translational Immunology, UMR 1064, 2CHU Nantes, Nantes Université, Department of Pediatric and Congenital Cardiac Surgery, 3Nantes Université, CHU Nantes, INSERM, CNRS, BioCore, SFR Bonamy

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Thymus OrganoidsSelf-toleranceAutoimmunityThymic Epithelial CellsThymopoiesisCell TherapyAutoimmune DiseasesExtracellular MatrixInduced Pluripotent Stem CellsThree-dimensional HydrogelsThymocyte ProgenitorsMicroenvironment ModelingCellular CompositionOrgan TransplantationFunctional T Cell Repertoire

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d'Arco, M., Provin, N., Maminirina, P., Baron, O., Guillonneau, C., David, L., Giraud, M. Formation of Human Thymus Organoids in Three-Dimensional Fibrin Hydrogels. J. Vis. Exp. (212), e66795, doi:10.3791/66795 (2024).

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