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In vitro myelinisatie van perifere axonen in een cocultuur van dorsale wortel ganglionexplantaten en Schwann-cellen
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Neuroscience
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JoVE Journal Neuroscience
In Vitro Myelination of Peripheral Axons in a Coculture of Rat Dorsal Root Ganglion Explants and Schwann Cells
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In vitro myelinisatie van perifere axonen in een cocultuur van dorsale wortel ganglionexplantaten en Schwann-cellen

Nederlands

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1,670 Views

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08:57 min

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February 10, 2023

DOI:

10.3791/64768-v

DOI:
10.3791/64768-v

•

08:57 min
February 10, 2023

•

2 Views
, , , , , ,
1Department of Neurology,Ruhr-University Bochum, St. Josef Hospital

Summary

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In het cocultuursysteem van dorsale wortelganglia en Schwann-cellen kan myelinisatie van het perifere zenuwstelsel worden bestudeerd. Dit model biedt experimentele mogelijkheden om perifere myelinisatie te observeren en te kwantificeren en om de effecten van interessante verbindingen op de myelineschede te bestuderen.

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Cite this Article

Blusch, A., Sgodzai, M., Rilke, N., Motte, J., König, J., Pitarokoili, K., Grüter, T. In Vitro Myelination of Peripheral Axons in a Coculture of Rat Dorsal Root Ganglion Explants and Schwann Cells. J. Vis. Exp. (192), e64768, doi:10.3791/64768 (2023).

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