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Use of In Vivo Imaging to Screen for Morphogenesis Phenotypes in Candida albicans Mutant Strains During Active Infection in a Mammalian Host
JoVE Journal
Immunology and Infection
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JoVE Journal Immunology and Infection
Use of In Vivo Imaging to Screen for Morphogenesis Phenotypes in Candida albicans Mutant Strains During Active Infection in a Mammalian Host

Use of In Vivo Imaging to Screen for Morphogenesis Phenotypes in Candida albicans Mutant Strains During Active Infection in a Mammalian Host

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1,598 Views

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09:24 min

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October 12, 2022

DOI:

10.3791/64258-v

DOI:
10.3791/64258-v

•

09:24 min
October 12, 2022

•

8 Views
, ,
1Department of Pediatrics, Carver College of Medicine,University of Iowa, 2Department of Microbiology and Immunology, Carver College of Medicine,University of Iowa

Summary

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This manuscript describes a method for screening moderately sized Candida albicans mutant libraries for morphogenesis phenotypes during active infection in a mammalian host using non-invasive confocal microscopy.

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Cite this Article

Wakade, R. S., Krysan, D. J., Wellington, M. Use of In Vivo Imaging to Screen for Morphogenesis Phenotypes in Candida albicans Mutant Strains During Active Infection in a Mammalian Host. J. Vis. Exp. (188), e64258, doi:10.3791/64258 (2022).

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