This manuscript describes a method for screening moderately sized Candida albicans mutant libraries for morphogenesis phenotypes during active infection in a mammalian host using non-invasive confocal microscopy.
Wakade, R. S., Krysan, D. J., Wellington, M. Use of In Vivo Imaging to Screen for Morphogenesis Phenotypes in Candida albicans Mutant Strains During Active Infection in a Mammalian Host. J. Vis. Exp. (188), e64258, doi:10.3791/64258 (2022).