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Use of In Vivo Imaging to Screen for Morphogenesis Phenotypes in Candida albicans Mutant Strains During Active Infection in a Mammalian Host
JoVE 杂志
免疫与感染
This content is Free Access.
JoVE 杂志 免疫与感染
Use of In Vivo Imaging to Screen for Morphogenesis Phenotypes in Candida albicans Mutant Strains During Active Infection in a Mammalian Host

Use of In Vivo Imaging to Screen for Morphogenesis Phenotypes in Candida albicans Mutant Strains During Active Infection in a Mammalian Host

1,598 Views

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09:24 min

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October 12, 2022

DOI:

10.3791/64258-v

DOI:
10.3791/64258-v

•

09:24 min
October 12, 2022

•

8 Views
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1Department of Pediatrics, Carver College of Medicine,University of Iowa, 2Department of Microbiology and Immunology, Carver College of Medicine,University of Iowa

Summary

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This manuscript describes a method for screening moderately sized Candida albicans mutant libraries for morphogenesis phenotypes during active infection in a mammalian host using non-invasive confocal microscopy.

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Cite this Article

Wakade, R. S., Krysan, D. J., Wellington, M. Use of In Vivo Imaging to Screen for Morphogenesis Phenotypes in Candida albicans Mutant Strains During Active Infection in a Mammalian Host. J. Vis. Exp. (188), e64258, doi:10.3791/64258 (2022).

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