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Behavior
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使用口面部操作性疼痛测定法评估大鼠神经损伤诱导的机械超敏反应
JoVE Journal
Behavior
This content is Free Access.
JoVE Journal
Behavior
Assessment of Nerve Injury-Induced Mechanical Hypersensitivity in Rats Using an Orofacial Operant Pain Assay
Please note that all translations are automatically generated.
Click here for the English version.
使用口面部操作性疼痛测定法评估大鼠神经损伤诱导的机械超敏反应
DOI:
10.3791/64221-v
•
07:39 min
•
July 26, 2022
•
Basak Donertas-Ayaz
,
Ariana C. Brice-Tutt
,
Wendi L. Malphurs
,
Darrice Montgomery
,
Richard H. Mills
,
John K. Neubert
,
Robert M. Caudle
1
Department of Oral and Maxillofacial Surgery
,
University of Florida, Gainesville
,
2
Department of Orthodontics
,
University of Florida, Gainesville
,
3
Stoelting Co. Wood Dale
Chapters
00:05
Introduction
00:52
Setting up the Orofacial Pain Assessment Device (Opad)
01:32
Setting up a Protocol and Creating an Experiment File
04:01
Training and Baseline Testing Sessions
05:06
Induction of Orofacial Neuropathic Pain and Evaluation of Mechanical Hypersensitivity
05:54
Results: The Assessment of Mechanical Hypersensitivity in a Rat Model
07:13
Conclusion
Summary
Automatic Translation
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Automatic Translation
该协议描述了使用基于操作者的口面部疼痛评估装置在神经性口面部疼痛大鼠模型中评估机械超敏反应。
Tags
Orofacial Pain Assessment Device
OPAD
Operant Reward Conflict Paradigm
Nociception
Learning
Motivation
Translational Validity
Reflex-based Assays
Infraorbital Nerve
CCI Surgery
Mechanical Hypersensitivity
Rat
Preclinical Pain Research
Automated
Experimenter Bias
Protocol Setup
Apparatus
Equipment Modes
Testing Stages
Treatment Groups
Animal ID
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