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Assessment of Nerve Injury-Induced Mechanical Hypersensitivity in Rats Using an Orofacial Operant Pain Assay
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Behavior
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JoVE Journal Behavior
Assessment of Nerve Injury-Induced Mechanical Hypersensitivity in Rats Using an Orofacial Operant Pain Assay

Assessment of Nerve Injury-Induced Mechanical Hypersensitivity in Rats Using an Orofacial Operant Pain Assay

2,984 Views

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07:39 min

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July 26, 2022

DOI:

10.3791/64221-v

DOI:
10.3791/64221-v

•

07:39 min
July 26, 2022

•

1 Views
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1Department of Oral and Maxillofacial Surgery,University of Florida, Gainesville, 2Department of Orthodontics,University of Florida, Gainesville, 3Stoelting Co. Wood Dale

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Orofacial Pain Assessment DeviceOPADOperant Reward Conflict ParadigmNociceptionLearningMotivationTranslational ValidityReflex-based AssaysInfraorbital NerveCCI SurgeryMechanical HypersensitivityRatPreclinical Pain ResearchAutomatedExperimenter BiasProtocol SetupApparatusEquipment ModesTesting StagesTreatment GroupsAnimal ID

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Donertas-Ayaz, B., Brice-Tutt, A. C., Malphurs, W. L., Montgomery, D., Mills, R. H., Neubert, J. K., Caudle, R. M. Assessment of Nerve Injury-Induced Mechanical Hypersensitivity in Rats Using an Orofacial Operant Pain Assay. J. Vis. Exp. (185), e64221, doi:10.3791/64221 (2022).

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