This protocol describes the assessment of mechanical hypersensitivity in a rat model of neuropathic orofacial pain using an operant-based orofacial pain assessment device.
Donertas-Ayaz, B., Brice-Tutt, A. C., Malphurs, W. L., Montgomery, D., Mills, R. H., Neubert, J. K., Caudle, R. M. Assessment of Nerve Injury-Induced Mechanical Hypersensitivity in Rats Using an Orofacial Operant Pain Assay. J. Vis. Exp. (185), e64221, doi:10.3791/64221 (2022).